Zoloft is an antidepressant medication used to treat a variety of conditions, including depression and other mental/mood disorders. It helps prevent suicidal thoughts/attempts as well as providing other important benefits. It is part of a group of drugs called selective serotonin reuptake inhibitors. These affect chemicals in the brain that may become unbalanced and cause depression. Zoloft may also be used to treat PTSD and PMDD.


Side effects may include nausea, dizziness, drowsiness, dry mouth, loss of appetite, increased sweating, diarrhea, upset stomach, or trouble sleeping. Unlikely, but serious side effects may include easy bruising/bleeding, decrease in sexual ability, muscle cramps, shaking, or unusual weight loss. Zoloft may also increase serotonin levels and rarely cause a serious condition called serotonin syndrome.


Zoloft has been linked to numerous lawsuits involving serious birth defects. Pfizer, Zoloft’s manufacturer, has been accused of advertising the drug to pregnant women even though it has been shown to increase the risk of birth defects such as holes in the heart, cleft palate, club feet, skull defects and more. More than 250 lawsuits are already pending from those seeking compensation from damages associated with Zoloft.